CBD is the next best known cannabinoid next to THC. Cannabis naturally synthesizes
CBDA from CBGA, and once heated it becomes become CBD. Unlike THC, CBD is not
psychoactive, however it does possess sedative properties. CBD is well known for its extensive
medicinal value. While studies are not complete, scientists have determined that isolated CBD
is able to provide relief from nausea, vomiting, tumor growth, anxiety, depression,
neurogenerative disorders, epilepsy, convulsions, and immunity issues. CBD is also reported to
lower prostaglandin levels in the body which can help reduce the cramps, pain, and
inflammation associated with menstruation. Clinical trials have also shown that CBD can reduce
the anxiety, memory loss and other adverse side effects reported, after consuming or inhaling
too much THC.
The CBC that results from the decarboxylation of CBCA is non-psychoactive. CBC binds
with the endocannabinoid receptors in the body associated with pain perception, making it an
effective pain reliver. Next to CBG, CBC is the next most potent cannabinoid at inhibiting new
cancer cell growth. Studies show that CBC has a positive effect on the cells that are responsible
for brain function and homeostasis. These specific brain cells are very important as they
counteract the oxidative stress, toxicity, and inflammation that create neurogenerative diseases
like Alzheimer’s. Studies have shown that CBC reduces the inflammation and excessive lipid
production in the sebaceous glands that associated with bad acne. CBC is also a powerful
antibacterial and anti-fungal, making it very useful as a topical. Other studies have shown that
CBC, when combined with THC and CBD, has a powerful anti-depressant value.
The cannabinoid CBN should be understood as the degradation product of THC.
Prolonged exposure to air, due to improper storage, can cause the THCA in dried cannabis to
become CBNA, which becomes the highly medicinal cannabinoid CBN upon decarboxylation.
CBN has also be researched far less than THC and CBD, and like CBG, its medicinal value is
slowly being recognized. Limited studies of CBN have demonstrated that it is useful in sedation,
appetite stimulation, treatment of glaucoma, pain relief, fighting MRSA bacteria, immune
function treatment, treatment of insomnia and anxiety, and treatment of bone disorders. As a
by-product of THC, CBN can have mildly psychoactive properties and has value as a potent anti-
convulsant. CBN is considered partially responsible for the sedative effects of cannabis. If the
medicinal effects of CBN are what you are after, simply leave some of your flower out and
unsealed, exposed to the air, and its THCA will naturally covert to CBNA, and then to CBN when
you smoke it.
Most of the research and reported physiological effects discussed above is based on
studies performed on isolated cannabinoids, meaning THC or CBD alone. Some studies of THC
and CBD combined show that together they are a more potent anti-tumor force than either is
alone, as well as a stronger pain reliever. As mentioned before, consuming CBD with THC can
help mitigate the feeling of being “too high” after smoking or eating too much THC. Studies on
all the cannabinoids combined, such as the way they occur naturally in cannabis, are very
limited as cannabis is still federally illegal. One can only assume that combined together,
cannabinoids are far more potent and medicinally valuable than they are alone.